Éloge France Vietnam – Cooperate and develop functional food dosage forms such as: tablets, capsules, powders and granules…
Tablets
Currently, tablets are a popular and popular solid dosage form. Each tablet is a dosage unit, used to chew, drink, suck, place or mix in water to drink… There are two main types of tablets: Tablets and round tablets (complete tablets). Tablets are a form of solid medicine prepared by compressing one or more types of pharmaceutical ingredients with or without adding excipients such as adhesive filler excipients, disintegrating excipients, adhesive excipients, slippery excipients, coated excipients… cylindrical in shape. flat, oblong or other shapes.
Tablets are widely used because they have many outstanding advantages. In terms of use, the general advantage of the tablet form is that the dose is divided into 1 time relatively accurately, the volume is often compact and light, in solid form, transportation; Use becomes easy, very convenient and simple. Wide range of uses: can be swallowed, chewed, sucked, mixed into a solution or suspension for drinking… In addition, there may be characters on the tablet’s surface to identify the product name. In terms of technology, the active ingredients in tablets are also more stable and have a longer lifespan than liquid or powder forms due to limited contact of the active ingredients with factors that promote decomposition reactions such as oxygen, air, water or moisture. Tablets can combine multiple active ingredients.
Tablets easily hide the unpleasant taste of the active ingredient because the compression of the active ingredient itself with excipients helps limit the taste and in particular, many film coating technologies can be used to increase aesthetics and minimize Many unpleasant flavors. In addition, many advanced technologies can be applied to help protect the active ingredients such as moisture-proof coating, enteric coating, or technologies to control the release of active ingredients to help prolong the duration of action or localize the effect at the target. . Finally, in terms of production, this is a form that is easy to invest in large production, helping to lower product costs. In addition to the above advantages, tablets also have the following disadvantages: Not all medicinal substances can be prepared into tablets. After pressing the tablet due to the effect of compression force, and possibly excipients, the contact area of the drug with the dissolution medium is reduced. With poorly soluble or poorly soluble active ingredients, the bioavailability of the active ingredient will be reduced. . During the tablet preparation process, depending on the technology used, the stability of the active ingredient can still be affected by factors during the preparation process such as compression force, humidity, heat, excipients…
Round tablets are spherical solids prepared from active ingredient powder, medicinal herbs or medicinal extracts and excipients in a certain volume, used for oral administration. The round pill form is most commonly found in the preparation of oriental medicine or functional foods from medicinal herbs. In addition to the general advantages of solid tablets such as stable active ingredients, little degradation, can combine many types of active ingredients, compact volume, easy to transport and preserve, round tablets can also apply other technologies. The coating helps hide the taste of the active ingredient, protect the active ingredient or localize the effect. Round tablets have the following main advantages: simple preparation technique, does not require complicated equipment, and is easy to produce. Regarding disadvantages, difficulty in standardizing quality is the main weakness of this form due to large volume variation. In particular, herbal medicines are prepared from herbs whose active ingredients are unknown, making quality assessment difficult. In addition, pellets prepared on a small scale are difficult to ensure hygiene.
Cystic form
Capsules are a divided dosage dosage form consisting of 2 parts: the capsule shell and a dosage unit of the active ingredient prepared in an appropriate form. The empty capsule is attached to the drug and introduced into the body with the drug. After releasing the drug, the capsule is digested in the body. Active ingredients can be prepared in the form of solutions, suspensions, powders, granules, even tablets… Capsules are divided into two types: Hard capsules (hard capsule shell consists of 2 parts: body and lid that fit tightly together). ) and soft cysts (the capsule shell is a unified, soft and flexible mass).
In terms of use, the capsule form has the advantage of being easy to swallow due to its oblong shape and shiny capsule surface; Convenient to use and easy to store and transport because it has been dosed and packaged compactly like tablets. In terms of production, capsules are easy to apply to large, high-yield production. High bioavailability due to simple formulations with few excipients and less impact of preparation techniques compared to tablets; The capsule shell usually disintegrates easily to release the drug. However, with active ingredients that irritate the digestive tract, capsules should not be encapsulated because after the capsule ruptures, it will be released massively, leading to a high concentration of active ingredients at the site of release, causing strong irritation at that point.
Granules and powder form
Powder is a dry solid dosage form, prepared from one or more powders (active ingredients or herbal extracts) of determined size by mixing well into a homogeneous mixture, for oral or external use. The main advantage of this form is that the technique is simple and does not require complexity. Solid form makes it easy to pack and transport. There are fewer interactions and incompatibilities than liquid forms, so many different active ingredients can be combined in the same formula.
The press process is not affected by heat, moisture, or compression; Relatively durable in storage; extended lifespan; Suitable for active ingredients that are easily hydrolyzed, easily oxidized, and easily degraded during the production process. In addition, due to the large contact area, not affected by compression force and adhesive excipients, it easily dissolves and releases the active ingredients, so bioavailability is higher than other solid drug forms. However, the large contact area makes it easy to absorb moisture, so the packaging needs to have good moisture resistance. Some sensitive active ingredients need to be packed in vacuum packaging to limit the contact of the active ingredients. with air and water vapor.
Granules are solid dosage forms, usually prepared from active ingredient powder and sticky excipients to form small porous particles 1-2 cm in diameter. Granules are a form especially suitable for children. The granule form has the same advantages as the powder form, however the preparation technique is more complicated and during the preparation process the active ingredients can be affected by factors such as heat and humidity at certain stages. .
Above we have shared with you some dosage forms of functional foods. If you want to know more about functional foods made from natural ingredients that are safe for your health, please quickly contact the Éloge France Vietnam factory for free consultation.